Description

GenieFluor 488 Anti-Rat CD8a Antibody [OX-8]

The GenieFluor 488 Anti-Rat CD8a Antibody (OX-8) offered by AssayGenie is a cutting-edge tool designed for precise and reliable detection of CD8a, a crucial cell surface marker involved in immune responses in rats. This antibody, meticulously developed for optimal performance, specifically targets the CD8a protein and allows for robust visualization and analysis in various experimental settings.Rigorously validated and highly reactive with rat samples, the GenieFluor 488 Anti-Rat CD8a Antibody (OX-8) is a versatile research reagent ideal for a wide range of immunological studies. Its application extends to immunophenotyping, flow cytometry, immunofluorescence, and other techniques, enabling detailed examination of CD8a expression patterns and functions in different biological contexts.

By utilizing the GenieFluor 488 Anti-Rat CD8a Antibody (OX-8), researchers can deepen their understanding of immune cell subsets, T lymphocyte responses, and immune system dynamics in rat models. This antibody opens up new possibilities for investigating immune-mediated processes, infectious diseases, autoimmune conditions, and beyond, providing valuable insights that can drive advancements in immunotherapy and immunological research.

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Product Title:	GenieFluor 488 Anti-Rat CD8a Antibody [OX-8]
SKU:	AGEL2199
Size:	50 Tests, 100 Tests, 200 Tests
Clone No:	OX-8
Synonyms:	T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:	Mouse
Reactivity:	Rat
Application:	FCM

Isotype:	Mouse IgG1, κ
Isotype Control:	Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:	Liquid
Conjugation:	Genie Fluor488
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:

Swissprot:	P07725
Gene ID:	24930
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:	CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2, and CD8α. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages, and some activated CD4+ T cells (not resting). CD8a forms heterodimers with the CD8β chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 αβ heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck).

GenieFluor 488 Anti-Rat CD8a Antibody [OX-8] (AGEL2199)

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Description