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GenieFluor Red 780 Anti-Mouse H-2 Antibody [M1/42] (AGEL3099)

Datasheet MSDS
SKU AGEL3099
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Mouse
Host Species Rat
Isotype Rat IgG2a, κ
Clone M1/42
Conjugation AFRed 780
€139 - €413

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Description

system_update_altDatasheetsystem_update_altMSDS

GenieFluor Red 780 Anti-Mouse H-2 Antibody [M1/42]

The GenieFluor Red 780 Anti-Mouse H-2 Antibody (M1/42) is a highly specialized antibody designed for research involving the mouse H-2 antigen. This antibody, specifically raised for use in mouse samples, is validated for various applications including flow cytometry, immunohistochemistry, and immunofluorescence, allowing for precise detection and analysis of the H-2 antigen across different experimental settings.The H-2 antigen, a major histocompatibility complex (MHC) molecule, plays a pivotal role in immune recognition and response in mice. It is crucial for antigen presentation to T cells, governing adaptive immune responses and influencing immune tolerance and autoimmunity.

Understanding the expression and function of the H-2 antigen is essential for investigating immune responses, transplant rejection, infectious diseases, and autoimmune conditions in mouse models.The GenieFluor Red 780 Anti-Mouse H-2 Antibody (M1/42) provides researchers with a powerful tool to explore the intricacies of immune regulation and host-pathogen interactions in murine systems. Its high specificity and sensitivity make it an ideal choice for studies in immunology, infectious diseases, transplantation research, and drug development, enabling precise and reliable detection of the H-2 antigen in diverse biological samples.

Product Title:GenieFluor Red 780 Anti-Mouse H-2 Antibody [M1/42]
SKU:AGEL3099
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M1/42
Synonyms:Mouse major histocompatibility complex (MHC) H-2; MHC I;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor Red 780 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie FluorRed 780
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:111364
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:The M1/42 antibody reacts with the H-2 MHC class I alloantigens expressed on nucleated cells from mice of the a, b, d, j, k, s, and u haplotypes (Stallcup, KC et al, 1981). MHC class I is involved in antigen presentation to T cells expressing CD3/TCR and CD8 proteins.
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