Description

GenieFluor Violet 450 Anti-Human/Mouse CD44 Antibody [IM7]

The GenieFluor Violet 450 Anti-Human/Mouse CD44 Antibody (IM7) is a cutting-edge tool designed for researchers studying CD44, a cell surface glycoprotein involved in cell adhesion and migration. This antibody, optimized for use in flow cytometry and immunofluorescence applications, is highly specific and sensitive, enabling precise detection of CD44 expression in both human and mouse samples.CD44 is a versatile molecule with diverse functions in cell signaling, proliferation, and differentiation. Its role in cancer progression, stem cell biology, and immune responses makes it a key target for investigation in various research fields. By using the GenieFluor Violet 450 Anti-Human/Mouse CD44 Antibody, researchers can accurately analyze CD44 expression levels and distribution in different cell types, providing crucial insights into its involvement in physiological and pathological processes.

This high-quality antibody, validated for its performance and reliability, offers researchers a powerful tool for studying CD44 biology and its implications in health and disease. Whether investigating cancer metastasis, tissue regeneration, or immune cell interactions, the GenieFluor Violet 450 Anti-Human/Mouse CD44 Antibody (IM7) provides a valuable resource for advancing scientific understanding and potentially uncovering new therapeutic targets.

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Product Title:	GenieFluor Violet 450 Anti-Human/Mouse CD44 Antibody [IM7]
SKU:	AGEL2719
Size:	20 Tests, 100 Tests, 200 Tests
Clone No:	IM7
Synonyms:	CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:	Rat
Reactivity:	Human;Mouse
Application:	FCM

Isotype:	Rat IgG2b, κ
Isotype Control:	Genie Fluor Violet 450 Rat IgG2b, κ Isotype Control[LTF-2]
Form:	Liquid
Conjugation:	Genie FluorViolet 450
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:

Swissprot:	P15379 P16070
Gene ID:	12505,960
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:	CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

GenieFluor Violet 450 Anti-Human/Mouse CD44 Antibody [IM7] (AGEL2719)

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Description