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Anti-GPS1 Antibody (CAB6917)

SKU:
CAB6917
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 10 Anti-GPS1 Antibody CAB6917
  • Cell Biology Antibodies 10 Anti-GPS1 Antibody CAB6917
  • Cell Biology Antibodies 10 Anti-GPS1 Antibody CAB6917
  • Cell Biology Antibodies 10 Anti-GPS1 Antibody CAB6917
  • Cell Biology Antibodies 10 Anti-GPS1 Antibody CAB6917
€139 - €419
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Description

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Antibody Name:Anti-GPS1 Antibody
Antibody SKU:CAB6917
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 258-527 of human GPS1 (NP_997657.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Reactivity:Human, Mouse
Positive Samples:293T, SKOV3, Mouse brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 258-527 of human GPS1 (NP_997657.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VSKA ESTP EIAE QRGE RDSQ TQAI LTKL KCAA GLAE LAAR KYKQ AAKC LLLA SFDH CDFP ELLS PSNV AIYG GLCA LATF DRQE LQRN VISS SSFK LFLE LEPQ VRDI IFKF YESK YASC LKML DEMK DNLL LDMY LAPH VRTL YTQI RNRA LIQY FSPY VSAD MHRM AAAF NTTV AALE DELT QLIL EGLI SARV DSHS KILY ARDV DQRS TTFE KSLL MGKE FQRR AKAM MLRA AVLR NQIH VKSP PREG SQGE LTPA NSQS RMST NM
Gene ID:2873
Uniprot:Q13098
Cellular Location:Cytoplasm, Nucleus
Calculated MW:55kDa/59kDa
Observed MW:55kDa
Synonyms:GPS1, COPS1, CSN1, SGN1
Background:This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells.
UniProt Protein Function:COPS1: a protein that suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction. Shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells.
UniProt Protein Details:

Protein type:G protein regulator, misc.

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: signalosome; cytoplasm; nucleus

Molecular Function:protein binding; GTPase inhibitor activity

Biological Process: cullin deneddylation; JNK cascade; cell cycle; inactivation of MAPK activity

NCBI Summary:This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:Q13098
NCBI GenInfo Identifier:223590263
NCBI Gene ID:2873
NCBI Accession:Q13098.4
UniProt Secondary Accession:Q13098,Q8NA10, Q9BWL1,
UniProt Related Accession:Q13098
Molecular Weight:491
NCBI Full Name:COP9 signalosome complex subunit 1
NCBI Synonym Full Names:G protein pathway suppressor 1
NCBI Official Symbol:GPS1  
NCBI Official Synonym Symbols:CSN1; COPS1  
NCBI Protein Information:COP9 signalosome complex subunit 1; SGN1; GPS-1; signalosome subunit 1; COP9 signalosome subunit 1; JAB1-containing signalosome subunit 1
UniProt Protein Name:COP9 signalosome complex subunit 1
UniProt Synonym Protein Names:G protein pathway suppressor 1; GPS-1; JAB1-containing signalosome subunit 1; Protein MFH
UniProt Gene Name:GPS1  
UniProt Entry Name:CSN1_HUMAN
Anti-GPS1 Antibody (CAB6917)Western blot analysis of extracts of various cell lines, using GPS1 antibody (CAB6917) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
Anti-GPS1 Antibody (CAB6917)Immunohistochemistry of paraffin-embedded human kidney using GPS1 antibody (CAB6917) at dilution of 1:100 (40x lens).
Anti-GPS1 Antibody (CAB6917)Immunohistochemistry of paraffin-embedded human stomach using GPS1 antibody (CAB6917) at dilution of 1:100 (40x lens).
Anti-GPS1 Antibody (CAB6917)Immunohistochemistry of paraffin-embedded mouse cancer using GPS1 antibody (CAB6917) at dilution of 1:100 (40x lens).
Anti-GPS1 Antibody (CAB6917)Immunofluorescence analysis of MCF7 cells using GPS1 antibody (CAB6917).

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