The GSTT1 Monoclonal Antibody (CAB23070) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced using state-of-the-art technology, specifically targets the GSTT1 protein and is highly sensitive and specific in detecting its presence in human samples.GSTT1 is a crucial enzyme involved in the metabolism and elimination of various toxins and carcinogens, making it a target of interest in research on drug metabolism, environmental toxicology, and cancer biology. This monoclonal antibody allows for the precise detection and quantification of GSTT1 levels in different cell types, tissues, and biological samples, making it an invaluable tool for understanding the mechanisms of detoxification and their implications in health and disease.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
GSTT1 Monoclonal Antibody
SKU:
CAB23070
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC59201
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:1000 - 1:5000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
GSTT1
Positive Sample:
HepG2, Mouse Liver, Mouse kindey, Rat Brain, Rat Liver
Cellular Localization:
Cytoplasm.
Calculated MW:
27kDa
Observed MW:
27kDa
The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
2952
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using GSTT1 Rabbit mAb (CAB23070) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
