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HAdV-3 Protease/L3 Recombinant Protein (C-His)
Key Features

HAdV-3 Protease/L3 Recombinant Protein (C-His) (GXRP07935)

SKU GXRP07935
Product Type Recombinant Protein
Species HAdV-3
Expression System E. coli
Tag C-His
$458 - $2,412

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Description

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HAdV-3 Protease/L3 Recombinant Protein (C-His)

HAdV-3 Protease/L3 Recombinant Protein (C-His) is a recombinant protein expressed in E. coli, spanning Met1-Gln209, with a C-terminal His tag. Predicted molecular weight: 24.86 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Protease (L3) is a ~23 kDa protein. Cleaves viral precursor proteins (pTP, pIIIa, pVI, pVII, pVIII, and pX) inside newly assembled particles giving rise to mature virions. For research use only.

Protease complexed to its cofactor slides along the viral DNA to specifically locate and cleave the viral precursors. Mature virions have a weakened organization compared to the unmature virions, thereby facilitating subsequent uncoating. Without maturation, the particle lacks infectivity and is unable to uncoat. Late in adenovirus infection, in the cytoplasm, may participate in the cytoskeleton destruction.

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