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KAT1/HAT1 Rabbit Polyclonal Antibody (CAB6188)

SKU:
CAB6188
Product Type:
Antibody
Applications:
WB
IHC
IF
IP
ChIP
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 10 Anti-HAT1 Antibody CAB6188
  • Cell Biology Antibodies 10 Anti-HAT1 Antibody CAB6188
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:KAT1/HAT1 Rabbit Polyclonal Antibody
SKU:CAB6188
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 245-419 of human KAT1/KAT1/HAT1 (NP_003633.1).
Sequence:TPFQ GQGH GAQL LETV HRYY TEFP TVLD ITAE DPSK SYVK LRDF VLVK LCQD LPCF SREK LMQG FNED MAIE AQQK FKIN KQHA RRVY EILR LLVT DMSD AEQY RSYR LDIK RRLI SPYK KKQR DLAK MRKC LRPE ELTN QMNQ IEIS MQHE QLEE SFQE LVED YRRV IERL AQE
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200
Synonyms:KAT1; KAT1/HAT1
Positive Sample:MCF7,SW480,Jurkat,293T,HeLa,HepG2,U-251MG,Mouse spleen,Rat testis
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus, Nucleus matrix, nucleoplasm.
Calculated MW:50kDa
Observed MW:50kDa

The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.

Purification Method:Affinity purification
Gene ID:8520
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using KAT1/HAT1 Rabbit pAb (CAB6188) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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