Anti-KAT13A / SRC1 Antibody (CAB9058)
- SKU:
- CAB9058
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- F-SRC-1
- KAT13A
- RIP160
- SRC1
- bHLHe42
- bHLHe74
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Product Name: | KAT13A / SRC1 Rabbit mAb |
| Product Code: | CAB9058 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74 |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human KAT13A / SRC1 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HeLa, 293T, SGC-7901 |
| Immunogen: | A synthesized peptide derived from human KAT13A / SRC1 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 8648 |
| Uniprot: | Q15788 |
| Calculated MW: | 157kDa |
| Observed MW: | 180KDa |
| UniProt Protein Function: | SRC-1: a transcriptional coactivator for steroid and nuclear hormone receptors. A member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, and bHLH and PAS domains. Phosphorylated and activated via the mitogen-activated protein kinase pathway. Three alternatively spliced isoforms have been described. |
| UniProt Protein Details: | Protein type:DNA-binding; Acetyltransferase; Oncoprotein; EC 2.3.1.48; Nuclear receptor co-regulator; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 2p23 Cellular Component: nucleoplasm; neuron projection; nuclear chromatin; cytoplasm Molecular Function:ligand-dependent nuclear receptor binding; protein dimerization activity; transcription coactivator activity; protein N-terminus binding; retinoid X receptor binding; signal transducer activity; protein binding; histone acetyltransferase activity; enzyme binding; ligand-dependent nuclear receptor transcription coactivator activity; androgen receptor binding; protein complex binding; estrogen receptor binding; chromatin binding; progesterone receptor binding; nuclear hormone receptor binding Biological Process: lactation; hypothalamus development; positive regulation of transcription from RNA polymerase II promoter by galactose; male mating behavior; intracellular receptor-mediated signaling pathway; response to retinoic acid; transcription, DNA-dependent; positive regulation of apoptosis; positive regulation of transcription, DNA-dependent; male gonad development; hippocampus development; positive regulation of female receptivity; cellular lipid metabolic process; response to estradiol stimulus; cellular response to hormone stimulus; ovulation cycle; androgen receptor signaling pathway; cerebellum development; positive regulation of transcription from RNA polymerase II promoter; cerebral cortex development; positive regulation of neuron differentiation; response to progesterone stimulus |
| NCBI Summary: | The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15788 |
| NCBI GenInfo Identifier: | 158518533 |
| NCBI Gene ID: | 8648 |
| NCBI Accession: | Q15788.3 |
| UniProt Related Accession: | Q15788 |
| Molecular Weight: | |
| NCBI Full Name: | Nuclear receptor coactivator 1 |
| NCBI Synonym Full Names: | nuclear receptor coactivator 1 |
| NCBI Official Symbol: | NCOA1Â Â |
| NCBI Official Synonym Symbols: | SRC1; KAT13A; RIP160; F-SRC-1; bHLHe42; bHLHe74Â Â |
| NCBI Protein Information: | nuclear receptor coactivator 1 |
| UniProt Protein Name: | Nuclear receptor coactivator 1 |
| UniProt Synonym Protein Names: | Class E basic helix-loop-helix protein 74; bHLHe74; Protein Hin-2; RIP160; Renal carcinoma antigen NY-REN-52; Steroid receptor coactivator 1; SRC-1 |
| Protein Family: | Protein |
| UniProt Gene Name: | NCOA1Â Â |
| UniProt Entry Name: | NCOA1_HUMAN |
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