null

HDAC7 Rabbit Monoclonal Antibody (CAB13008)

SKU:
CAB13008
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Monoclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:HDAC7 Rabbit Monoclonal Antibody
SKU:CAB13008
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-198 of human HDAC7 (Q8WUI4).
Sequence:RPQR LHHH LFLA GLQQ QRSV EPMR LSMD TPMP ELQV GPQE QELR QLLH KDKS KRSA VASS VVKQ KLAE VILK KQQA ALER TVHP NSPG IPYR TLEP LETE GATR SMLS SFLP PVPS LPSD PPEH FPLR KTVS EPNL KLRY KPKK SLER RKNP LLRK ESAP PSLR RRPA ETLG DSS
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:HD7; HD7A; HDAC7A; HDAC7
Positive Sample:HeLa,K-562,Mouse lung,Mouse brain,Mouse heart,Rat testis
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:103kDa
Observed MW:90-130kDa

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:51564
Clone Number:ARC0713
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using HDAC7 Rabbit mAb (CAB13008) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

Related Products