Description
HHV2/HSV2 US8/Envelope glycoprotein E Recombinant Protein (C-His)
HHV2/HSV2 US8/Envelope glycoprotein E Recombinant Protein (C-His) is a recombinant protein expressed in mammalian cells, spanning Met1-Leu418, with a C-terminal His tag. Predicted molecular weight: 46.43 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Envelope glycoprotein E (US8) is a ~58 kDa protein. In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. For research use only.
Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system. Together with US9, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips.
| Product Name: | HHV2/HSV2 US8/Envelope glycoprotein E Recombinant Protein (C-His) |
| SKU: | GXRP07093 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | HSV-2 |
| Synonyms: | Envelope glycoprotein E, US8 |
| Tag: | C-His |
| Expression Host: | Mammalian cells |
| Protein Length: | Met1-Leu418 |
| Calculated MW: | 46.43 kDa |
| UniProt: | A8U6C0 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
