The HIBADH Polyclonal Antibody is a valuable tool for researchers studying the HIBADH protein, which plays a crucial role in the metabolism of fatty acids. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in various applications including Western blot. By binding specifically to the HIBADH protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies related to lipid metabolism, mitochondrial function, and metabolic diseases.HIBADH, also known as 3-hydroxyisobutyrate dehydrogenase, is a key enzyme involved in the degradation of valine, a branched-chain amino acid.
Dysregulation of HIBADH activity has been linked to metabolic disorders and diseases such as diabetes, obesity, and cardiovascular disease. Understanding the function and regulation of HIBADH is essential for developing targeted therapies and interventions to manage these conditions effectively.In summary, the HIBADH Polyclonal Antibody is a reliable tool for researchers investigating the role of HIBADH in metabolic pathways and associated diseases. Its high specificity and sensitivity make it a valuable asset in advancing our understanding of lipid metabolism and developing strategies for treating metabolic disorders.
Product Name:
HIBADH Polyclonal Antibody
SKU:
CAB21349
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 37-336 of human HIBADH (NP_689953.1).
This gene encodes a mitochondrial 3-hydroxyisobutyrate dehydrogenase enzyme. The encoded protein plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde.
Purification Method:
Affinity purification
Gene ID:
11112
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using HIBADH Rabbit pAb (CAB21349) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
