Description
Human A1CF Recombinant Protein (N-His)
Human A1CF Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gly389-Arg587, with an N-terminal His tag. Predicted molecular weight: 23.45 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. APOBEC1 complementation factor (A1CF) is a ~65 kDa protein. Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. For research use only.
Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay.
| Product Name: | Human A1CF Recombinant Protein (N-His) |
| SKU: | GXRP02932 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ACF, ASP, APOBEC1 complementation factor, A1CF, APOBEC1-stimulating protein |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gly389-Arg587 |
| Calculated MW: | 23.45 kDa |
| UniProt: | Q9NQ94 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
