Description
Human ABCB8 Recombinant Protein (N-His)
Human ABCB8 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Val472-Ser735, with an N-terminal His tag. Predicted molecular weight: 31 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Mitochondrial potassium channel ATP-binding subunit (ABCB8) is a ~79 kDa protein. ATP-binding subunit of the mitochondrial ATP-gated potassium channel (mitoK(ATP)). For research use only.
Together with pore-forming subunit CCDC51/MITOK of the mitoK(ATP) channel, mediates ATP-dependent potassium currents across the mitochondrial inner membrane. An increase in ATP intracellular levels closes the channel, inhibiting K(+) transport, whereas a decrease in ATP levels enhances K(+) uptake in the mitochondrial matrix. Plays a role in mitochondrial iron transport. Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes.
| Product Name: | Human ABCB8 Recombinant Protein (N-His) |
| SKU: | GXRP02957 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ATP-binding cassette sub-family B member 8, mitochondrial, Mitochondrial potassium channel ATP-binding subunit, Mitochondrial sulfonylurea-receptor, ABCB8, Mitochondrial ATP-binding cassette 1, MITOSUR, MABC1, M-ABC1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Val472-Ser735 |
| Calculated MW: | 31 kDa |
| UniProt: | Q9NUT2 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
