Description
Human ABR Recombinant Protein (N-His)
Human ABR Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ile285-Ser628, with an N-terminal His tag. Predicted molecular weight: 41.98 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Active breakpoint cluster region-related protein is a ~97 kDa protein. Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. For research use only.
The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form. The central Dbl homology (DH) domain functions as a guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1. Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form.
| Product Name: | Human ABR Recombinant Protein (N-His) |
| SKU: | GXRP11460 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ABR, Active breakpoint cluster region-related protein |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ile285-Ser628 |
| Calculated MW: | 41.98 kDa |
| UniProt: | Q12979 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
