The Human AIM2 (Absent in Melanoma 2) CLIA Kit is specifically designed for the accurate measurement of AIM2 levels in human samples, including serum, plasma, and cell culture supernatants. This kit offers high sensitivity and specificity, ensuring reliable and consistent results for various research applications.AIM2 is a critical protein involved in the innate immune response, particularly in detecting cytoplasmic DNA and activating inflammatory pathways. Dysregulation of AIM2 has been linked to various inflammatory diseases and autoimmune disorders, making it a valuable biomarker for studying these conditions and exploring potential therapeutic interventions. Overall, the Human AIM2 CLIA Kit provides researchers with a reliable tool for analyzing AIM2 levels in human samples, contributing to a better understanding of the immune response and potential treatment strategies for related diseases. For more information and to purchase the kit, visit the link provided.
Product Name:
Human AIM2 (Absent In Melanoma 2) CLIA Kit
SKU:
HUES01267
Size:
96 Assays
Detection Method:
Chemiluminescence
Assay type:
Sandwich-CLIA
Assay time:
3 h 30 min
Sensitivity:
18.75 pg/mL
Detection range:
31.25-2000 pg/mL
Reovery:
80%-120%
This kit uses a sandwich chemiluminescence immunoassay (CLIA) principle. The microplate is pre-coated with an antibody specific to the target protein. Standards or samples are added to the wells and bind to the immobilized antibody. A biotinylated detection antibody is then added, followed by HRP-conjugated streptavidin to form a sandwich complex. After washing to remove unbound components, a chemiluminescent substrate is added. The HRP enzyme catalyzes a light-emitting reaction. The intensity of the emitted light is directly proportional to the concentration of the target protein in the sample. The signal is measured using a luminometer, and the concentration of the analyte is calculated based on a standard curve.
