Description
Human ANO2 Recombinant Protein (N-His)
Human ANO2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg188-Ala365, with an N-terminal His tag. Predicted molecular weight: 23.19 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Anoctamin-2 (ANO2/TMEM16B) is a ~113 kDa protein. Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. For research use only.
Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.
| Product Name: | Human ANO2 Recombinant Protein (N-His) |
| SKU: | GXRP06415 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | C12orf3, ANO2, Transmembrane protein 16B, TMEM16B, Anoctamin-2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Arg188-Ala365 |
| Calculated MW: | 23.19 kDa |
| UniProt: | Q9NQ90 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
