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Human AP1AR Recombinant Protein (N-His-KSI)
Key Features

Human AP1AR Recombinant Protein (N-His-KSI) (GXRP13781)

SKU GXRP13781
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His-KSI
€347 - €1,827

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Description

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Human AP1AR Recombinant Protein (N-His-KSI)

Human AP1AR Recombinant Protein (N-His-KSI) is a recombinant protein expressed in E. coli, spanning Gly2-Arg302, with an N-terminal His-KSI tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. AP-1 complex-associated regulatory protein is a ~34 kDa protein. Necessary for adaptor protein complex 1 (AP-1)-dependent transport between the trans-Golgi network and endosomes. For research use only.

Regulates the membrane association of AP1G1/gamma1-adaptin, one of the subunits of the AP-1 adaptor complex. The direct interaction with AP1G1/gamma1-adaptin attenuates the release of the AP-1 complex from membranes. Regulates endosomal membrane traffic via association with AP-1 and KIF5B thus linking kinesin-based plus-end-directed microtubular transport to AP-1-dependent membrane traffic. May act as effector of AP-1 in calcium-induced endo-lysosome secretion.

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