Description
Human APBB1 Recombinant Protein (N-His)
Human APBB1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn362-Cys672, with an N-terminal His tag. Predicted molecular weight: 36.65 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Amyloid beta precursor protein binding family B member 1 is a ~77 kDa protein. Transcription coregulator that can have both coactivator and corepressor functions. For research use only.
Adapter protein that forms a transcriptionally active complex with the gamma-secretase-derived amyloid precursor protein (APP) intracellular domain. Plays a central role in the response to DNA damage by translocating to the nucleus and inducing apoptosis. May act by specifically recognizing and binding histone H2AX phosphorylated on 'Tyr-142' (H2AXY142ph) at double-strand breaks (DSBs), recruiting other pro-apoptosis factors such as MAPK8/JNK1. Required for histone H4 acetylation at double-strand breaks (DSBs).
| Product Name: | Human APBB1 Recombinant Protein (N-His) |
| SKU: | GXRP11135 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | APBB1, Amyloid beta precursor protein binding family B member 1, Amyloid-beta A4 precursor protein-binding family B member 1, FE65, Protein Fe65, RIR |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asn362-Cys672 |
| Calculated MW: | 36.65 kDa |
| UniProt: | O00213 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
