Description
Human APOBEC3A Recombinant Protein (C-His)
Human APOBEC3A Recombinant Protein (C-His) is a recombinant protein expressed in E. coli, spanning Met1-Asn199, with a C-terminal His tag. Predicted molecular weight: 24.08 kDa. Purity: >95% as determined by SDS-PAGE. Supplied lyophilized from PBS pH7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. DNA dC->dU-editing enzyme APOBEC-3A (ABC3A) is a ~23 kDa protein. DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. For research use only.
Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
| Product Name: | Human APOBEC3A Recombinant Protein (C-His) |
| SKU: | GXRP08455 |
| Size: | 50 µg, 100 µg, 1 mg |
| Synonyms: | EC:3.5.4.38, DNA dC->dU-editing enzyme APOBEC-3A, A3A, Phorbolin-1, APOBEC3A |
| Tag: | C-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Asn199 |
| Calculated MW: | 24.08 kDa |
| UniProt: | P31941 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >95% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from PBS pH7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
