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Human APOC1 Recombinant Protein (N-His)
Key Features

Human APOC1 Recombinant Protein (N-His) (GXRP00474)

SKU GXRP00474
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human APOC1 Recombinant Protein (N-His)

Human APOC1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser31-Ser83, with an N-terminal His tag. Predicted molecular weight: 8.51 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Apolipoprotein C-I (APOC1) is a ~9 kDa protein. Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. For research use only.

Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.

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