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Human ARFGAP1 Recombinant Protein (N-His)
Key Features

Human ARFGAP1 Recombinant Protein (N-His) (GXRP04805)

SKU GXRP04805
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human ARFGAP1 Recombinant Protein (N-His)

Human ARFGAP1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Gly121, with an N-terminal His tag. Predicted molecular weight: 16.07 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) is a ~44 kDa protein. GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). For research use only.

Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated.

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