Description
Human ARHGAP24 Recombinant Protein (N-His)
Human ARHGAP24 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala20-Lys331, with an N-terminal His tag. Predicted molecular weight: 37.96 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Rho GTPase-activating protein 24 is a ~84 kDa protein. Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. For research use only.
Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia.
| Product Name: | Human ARHGAP24 Recombinant Protein (N-His) |
| SKU: | GXRP10836 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ARHGAP24, FILGAP, FilGAP, Filamin-A-associated RhoGAP, RAC1- and CDC42-specific GTPase-activating protein of 72 kDa, RC-GAP72, Rho GTPase-activating protein 24, Rho-type GTPase-activating protein 24, RhoGAP of 73 kDa, Sarcoma antigen NY-SAR-88, p73RhoGAP |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ala20-Lys331 |
| Calculated MW: | 37.96 kDa |
| UniProt: | Q8N264 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
