Description
Human ARHGEF12 Recombinant Protein (N-His)
Human ARHGEF12 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn366-Gly556, with an N-terminal His tag. Predicted molecular weight: 24.80 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Rho guanine nucleotide exchange factor 12 is a ~173 kDa protein. Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. For research use only.
May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Promotes endothelial cell and actin stress fiber reorientation in response to mechanotransduction.
| Product Name: | Human ARHGEF12 Recombinant Protein (N-His) |
| SKU: | GXRP08612 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Rho guanine nucleotide exchange factor 12, Leukemia-associated RhoGEF, ARHGEF12 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asn366-Gly556 |
| Calculated MW: | 24.80 kDa |
| UniProt: | Q9NZN5 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
