Description
Human ARID4B Recombinant Protein (N-His)
Human ARID4B Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Gly143, with an N-terminal His tag. Predicted molecular weight: 18.05 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. AT-rich interactive domain-containing protein 4B is a ~147 kDa protein. Acts as a transcriptional repressor. For research use only.
May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. Plays a role in the regulation of epigenetic modifications at the PWS/AS imprinting center near the SNRPN promoter, where it might function as part of a complex with RB1 and ARID4A. Involved in spermatogenesis, together with ARID4A, where it functions as a transcriptional coactivator for AR (androgen receptor) and enhances expression of genes required for sperm maturation. Regulates expression of the tight junction protein CLDN3 in the testis, which is important for integrity of the blood-testis barrier.
| Product Name: | Human ARID4B Recombinant Protein (N-His) |
| SKU: | GXRP10844 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | 180 kDa Sin3-associated polypeptide, ARID domain-containing protein 4B, ARID4B, AT-rich interactive domain-containing protein 4B, BRCAA1, Breast cancer-associated antigen BRCAA1, Histone deacetylase complex subunit SAP180, RBBP1L1, RBP1L1, Retinoblastoma-binding protein 1-like 1, SAP180, Sin3-associated polypeptide p180 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Gly143 |
| Calculated MW: | 18.05 kDa |
| UniProt: | Q4LE39 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
