Description
Human ARNTL Recombinant Protein (N-His)
Human ARNTL Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu48-Leu320, with an N-terminal His tag. Predicted molecular weight: 33.17 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Basic helix-loop-helix ARNT-like protein 1 (ARNTL) is a ~68 kDa protein. Transcriptional activator which forms a core component of the circadian clock. For research use only.
The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. Consists of two major components: the central clock, residing in the suprachiasmatic nucleus (SCN) of the brain, and the peripheral clocks that are present in nearly every tissue and organ system. Both the central and peripheral clocks can be reset by environmental cues, also known as Zeitgebers (German for 'timegivers').
| Product Name: | Human ARNTL Recombinant Protein (N-His) |
| SKU: | GXRP03344 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Basic-helix-loop-helix-PAS protein MOP3, ARNTL, Member of PAS protein 3, PAS domain-containing protein 3, BMAL1, Aryl hydrocarbon receptor nuclear translocator-like protein 1, BHLHE5, Class E basic helix-loop-helix protein 5, bHLHe5, MOP3, Brain and muscle ARNT-like 1, bHLH-PAS protein JAP3, PASD3 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu48-Leu320 |
| Calculated MW: | 33.17 kDa |
| UniProt: | O00327 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |