Description
Human ARPC1B Recombinant Protein (N-His)
Human ARPC1B Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Lys372, with an N-terminal His tag. Predicted molecular weight: 43.11 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Actin-related protein 2/3 complex subunit 1B (ARPC1B) is a ~40 kDa protein. Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). For research use only.
The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
| Product Name: | Human ARPC1B Recombinant Protein (N-His) |
| SKU: | GXRP04922 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Actin-related protein 2/3 complex subunit 1B, p41-ARC, Arp2/3 complex 41 kDa subunit, ARC41, ARPC1B |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Lys372 |
| Calculated MW: | 43.11 kDa |
| UniProt: | O15143 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
