Description
Human ASIC2 Recombinant Protein (N-His)
Human ASIC2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln71-Lys421, with an N-terminal His tag. Predicted molecular weight: 42.29 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Acid-sensing ion channel 2 (ASIC2) is a ~57 kDa protein. Forms pH-gated trimeric sodium channels that act as postsynaptic excitatory sensors in the nervous system. For research use only.
Upon extracellular acidification, these channels generate rapid, transient inward currents that fully desensitize. Highly selective for sodium, they are permeable to other cations. By forming heterotrimeric channels with ASIC1, could contribute to synaptic plasticity, learning, and memory. Additionally, as acid sensors at nerve terminals, plays a role in mechanosensation and phototransduction.
| Product Name: | Human ASIC2 Recombinant Protein (N-His) |
| SKU: | GXRP04926 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | BNaC1, ACCN, ACCN1, Mammalian degenerin homolog, Acid-sensing ion channel 2, BNAC1, MDEG, Amiloride-sensitive brain sodium channel, Amiloride-sensitive cation channel 1, neuronal, ASIC2, Brain sodium channel 1, Amiloride-sensitive cation channel neuronal 1, BNC1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Gln71-Lys421 |
| Calculated MW: | 42.29 kDa |
| UniProt: | Q16515 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
