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Human ATAT1 Recombinant Protein (C-His)
Key Features

Human ATAT1 Recombinant Protein (C-His) (GXRP02428)

SKU GXRP02428
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag C-His
$458 - $2,412

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Description

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Human ATAT1 Recombinant Protein (C-His)

Human ATAT1 Recombinant Protein (C-His) is a recombinant protein expressed in E. coli, spanning Met1-Pro196, with a C-terminal His tag. Predicted molecular weight: 23.47 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Alpha-tubulin N-acetyltransferase 1 (ATAT1) is a ~46 kDa protein. Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. For research use only.

Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.

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