Description
Human ATG2B Recombinant Protein (N-His)
Human ATG2B Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Lys1792-Asp2078, with an N-terminal His tag. Predicted molecular weight: 34.21 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Autophagy-related protein 2 homolog B (ATG2B) is a ~232 kDa protein. Lipid transfer protein required for both autophagosome formation and regulation of lipid droplet morphology and dispersion. For research use only.
Tethers the edge of the isolation membrane (IM) to the endoplasmic reticulum (ER) and mediates direct lipid transfer from ER to IM for IM expansion. Binds to the ER exit site (ERES), which is the membrane source for autophagosome formation, and extracts phospholipids from the membrane source and transfers them to ATG9 (ATG9A or ATG9B) to the IM for membrane expansion. Lipid transfer activity is enhanced by WDR45/WIPI4, which promotes ATG2B-association with phosphatidylinositol 3-monophosphate (PI3P)-containing membranes.
| Product Name: | Human ATG2B Recombinant Protein (N-His) |
| SKU: | GXRP07658 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Autophagy-related protein 2 homolog B, ATG2B, C14orf103 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Lys1792-Asp2078 |
| Calculated MW: | 34.21 kDa |
| UniProt: | Q96BY7 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
