Description
Human ATL3 Recombinant Protein (N-His)
Human ATL3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Asp336, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Atlastin-3 is a ~60 kDa protein. Atlastin-3 (ATL3) is a membrane-anchored GTPase that mediates the GTP-dependent fusion of endoplasmic reticulum (ER) membranes, maintaining the continuous ER network. For research use only.
It facilitates the formation of three-way junctions where ER tubules intersect. Two atlastin-3 on neighboring ER tubules bind GTP and form loose homodimers through the GB1/RHD3-type G domains and 3HB regions. Upon GTP hydrolysis, the 3HB regions tighten, pulling the membranes together to drive their fusion. After fusion, the homodimer disassembles upon release of inorganic phosphate (Pi).
| Product Name: | Human ATL3 Recombinant Protein (N-His) |
| SKU: | GXRP13882 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | AT3, ATL-3, ATL3, Atlastin-3, EC:3.6.5.- |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Asp336 |
| UniProt: | Q6DD88 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
