Description
Human ATP2C2 Recombinant Protein (N-His)
Human ATP2C2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Glu388-Asp576, with an N-terminal His tag. Predicted molecular weight: 22.92 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Calcium-transporting ATPase type 2C member 2 is a ~103 kDa protein. ATP-driven pump that supplies the Golgi apparatus with Ca(2+) and Mn(2+) ions, both essential cofactors for processing and trafficking of newly synthesized proteins in the secretory pathway. For research use only.
Within a catalytic cycle, acquires Ca(2+) or Mn(2+) ions on the cytoplasmic side of the membrane and delivers them to the lumenal side. The transfer of ions across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation that shifts the pump conformation from inward-facing to outward-facing state. Induces Ca(2+) influx independently of its ATP-driven pump function. At the basolateral membrane of mammary epithelial cells, interacts with Ca(2+) channel ORAI1 and mediates Ca(2+) entry independently of the Ca(2+) content of endoplasmic reticulum or Golgi stores.
| Product Name: | Human ATP2C2 Recombinant Protein (N-His) |
| SKU: | GXRP11792 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | ATP2C2, ATPase 2C2, Ca(2+)/Mn(2+)-ATPase 2C2, Calcium-transporting ATPase type 2C member 2, EC:7.2.2.10, KIAA0703, SPCA2, Secretory pathway Ca(2+)-transporting ATPase type 2 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Glu388-Asp576 |
| Calculated MW: | 22.92 kDa |
| UniProt: | O75185 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
