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Human ATP8B3 Recombinant Protein (N-His)
Key Features

Human ATP8B3 Recombinant Protein (N-His) (GXRP09762)

SKU GXRP09762
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
€347 - €1,827

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Description

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Human ATP8B3 Recombinant Protein (N-His)

Human ATP8B3 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn503-Leu741, with an N-terminal His tag. Predicted molecular weight: 29.61 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Phospholipid-transporting ATPase IK is a ~146 kDa protein. P4-ATPase flippase which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. For research use only.

Phospholipid translocation also seems to be implicated in vesicle formation and in uptake of lipid signaling molecules. May be responsible for the maintenance of asymmetric distribution of phosphatidylserine (PS) in spermatozoa membranes. Involved in acrosome reactions and binding of spermatozoa to zona pellucida.

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