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Human B2M Recombinant Protein (N-His)
Key Features

Human B2M Recombinant Protein (N-His) (GXRP01894)

SKU GXRP01894
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
Purity >90% as determined by SDS-PAGE.
€347 - €1,827

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Description

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Human B2M Recombinant Protein (N-His)

Human B2M Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Gln22-Met119, with an N-terminal His tag. Predicted molecular weight: 13.91 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Beta-2-microglobulin (B2M/β2-MG) is a ~13 kDa protein. Component of the class I major histocompatibility complex (MHC). For research use only.

Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation.

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