Description
Human B4GALNT2 Recombinant Protein (N-His)
Human B4GALNT2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Thr324-Ala566, with an N-terminal His tag. Predicted molecular weight: 29.92 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Beta-1,4 N-acetylgalactosaminyltransferase 2 (B4GALNT2) is a ~63 kDa protein. Beta-1,4 N-acetylgalactosaminyltransferase involved in the biosynthesis of Sd(a) histo-blood group antigen. For research use only.
Catalyzes the transfer of N-acetylgalactosamine (GalNAc) group in a beta-1,4-linkage from UDP-GalNAc to the galactose residue of NeuAcalpha2->3Gal-R to form Sd(a) glycan epitope GalNAcbeta1->4(NeuAcalpha2->3)Gal-R. The Sd(a) epitope is carried in O- and N-linked glycoproteins and glycolipids, including O-linked core 1 structures on GYPA/glycophorin, SLC4A1 and SLC29A1 in erythrocytes, N-linked glycans attached to the Tamm-Horsfall glycoprotein UMOD/uromodulin in renal fluids, O-linked core 3 glycans on mucins in colon and neolactosides in gastric mucosa. Confers protection against influenza A virus strains that attach to NeuAcalpha2->3-carrying host receptors. Modifies N-glycan chains on host receptors and prevents virus entry into cells.
| Product Name: | Human B4GALNT2 Recombinant Protein (N-His) |
| SKU: | GXRP03265 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Beta-1, 4 N-acetylgalactosaminyltransferase 2, B4GALNT2, GALGT2, Sd(a) beta-1, 4-GalNAc transferase, UDP-GalNAc:Neu5Aca2-3Galb-R b1, 4-N-acetylgalactosaminyltransferase |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Thr324-Ala566 |
| Calculated MW: | 29.92 kDa |
| UniProt: | Q8NHY0 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
