Description
Human BABRA1 Recombinant Protein (N-His)
Human BABRA1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg64-Lys249, with an N-terminal His tag. Predicted molecular weight: 23.77 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Gamma-aminobutyric acid receptor subunit alpha-1 is a ~51 kDa protein. Alpha subunit of the heteropentameric ligand-gated chloride channel gated by Gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain. For research use only.
GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit interface(s). When activated by GABA, GABAARs selectively allow the flow of chloride anions across the cell membrane down their electrochemical gradient. Alpha-1/GABRA1-containing GABAARs are largely synaptic. Chloride influx into the postsynaptic neuron following GABAAR opening decreases the neuron ability to generate a new action potential, thereby reducing nerve transmission.
| Product Name: | Human BABRA1 Recombinant Protein (N-His) |
| SKU: | GXRP10595 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | GABA(A) receptor subunit alpha-1, GABAAR subunit alpha-1, GABRA1, Gamma-aminobutyric acid receptor subunit alpha-1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Arg64-Lys249 |
| Calculated MW: | 23.77 kDa |
| UniProt: | P14867, P62812, P62813 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
