Description
Human BAG3 Recombinant Protein (N-GST)
Human BAG3 Recombinant Protein (N-GST) is a recombinant protein expressed in E. coli, spanning Gly421-Ala498, with an N-terminal GST tag. Predicted molecular weight: 35.71 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. BAG family molecular chaperone regulator 3 (BAG3) is a ~61 kDa protein. Co-chaperone and adapter protein that connects different classes of molecular chaperones including heat shock proteins 70 (HSP70s), e.g. For research use only.
HSPA1A/HSP70 or HSPA8/HSC70, and small heat shock proteins (sHSPs), e.g. HSPB8. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from HSP70s, thereby triggering client protein release. Nucleotide release is mediated via BAG3 binding to the nucleotide-binding domain (NBD) of HSP70s, whereas client release is mediated via binding to the substrate-binding domain (SBD).
| Product Name: | Human BAG3 Recombinant Protein (N-GST) |
| SKU: | GXRP00327 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | Docking protein CAIR-1, BAG3, Bcl-2-associated athanogene 3, BAG family molecular chaperone regulator 3, Bcl-2-binding protein Bis, BAG-3, BIS |
| Tag: | N-GST |
| Expression Host: | E. coli |
| Protein Length: | Gly421-Ala498 |
| Calculated MW: | 35.71 kDa |
| UniProt: | O95817 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
