Recombinant Human BDNF Protein(His Tag) (RPES5971)
Important signaling molecule that activates signaling cascades downstream of NTRK2.During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Product Name:
Recombinant Human BDNF Protein(His Tag)
SKU:
RPES5971
Size:
100μg, 20μg, 500μg, 1mg
Species:
Human
Synonyms:
Abrineurin, ProBDNF
Tag:
C-His
Sequence:
Met1-Arg247
Expression Host:
HEK293 Cells
Accession:
P23560
Endotoxin:
< 1.0 EU/mg of the protein as determined by the LAL method
Purity:
> 85% as determined by reducing SDS-PAGE.
Calculated MW:
26 kDa
Observed MW:
26 kDa
Bio-Activity:
Not validated for activity
Form:
Lyophilized powder
Source:
HEK293 Cells-derived Human BDNF protein Met1-Arg247, with an C-terminal His
Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Reconstitution:
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Storage:
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to - 80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
