Description
Human BLNK Recombinant Protein (N-His)
Human BLNK Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ser65-Thr314, with an N-terminal His tag. Predicted molecular weight: 29.62 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. B-cell linker protein (BLNK) is a ~50 kDa protein. Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. For research use only.
Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes.
| Product Name: | Human BLNK Recombinant Protein (N-His) |
| SKU: | GXRP02629 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | SLP65, SLP-65, B-cell adapter containing a SH2 domain protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, BASH, Cytoplasmic adapter protein, B-cell adapter containing a Src homology 2 domain protein, BLNK, B-cell linker protein |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ser65-Thr314 |
| Calculated MW: | 29.62 kDa |
| UniProt: | Q8WV28 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
