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Human CACNA1D Recombinant Protein (N-His)
Key Features

Human CACNA1D Recombinant Protein (N-His) (GXRP02008)

SKU GXRP02008
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human CACNA1D Recombinant Protein (N-His)

Human CACNA1D Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Lys163, with an N-terminal His tag. Predicted molecular weight: 19.14 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Voltage-dependent L-type calcium channel subunit alpha-1D (CACNA1D) is a ~245 kDa protein. Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. For research use only.

The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines.

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