Description
Human CADM1 Recombinant Protein (N-His)
Human CADM1 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn46-Tyr331, with an N-terminal His tag. Predicted molecular weight: 34.80 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cell adhesion molecule 1 is a ~48 kDa protein. Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. For research use only.
Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca(2+)-independent manner. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM1 in vivo. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo.
| Product Name: | Human CADM1 Recombinant Protein (N-His) |
| SKU: | GXRP14114 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | CADM1, Cell adhesion molecule 1, IGSF4, IGSF4A, IgSF4, Immunoglobulin superfamily member 4, NECL-2, NECL2, Nectin-like protein 2, SYNCAM, SgIgSF, Spermatogenic immunoglobulin superfamily, SynCAM, Synaptic cell adhesion molecule, TSLC-1, TSLC1, Tumor suppressor in lung cancer 1 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Asn46-Tyr331 |
| Calculated MW: | 34.80 kDa |
| UniProt: | Q9BY67 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
