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Human CALHM6 Recombinant Protein (N-His)
Key Features

Human CALHM6 Recombinant Protein (N-His) (GXRP04403)

SKU GXRP04403
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human CALHM6 Recombinant Protein (N-His)

Human CALHM6 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Arg197-Ile309, with an N-terminal His tag. Predicted molecular weight: 15.49 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Calcium homeostasis modulator protein 6 (CALHM6) is a ~34 kDa protein. Pore-forming subunit of an ATP-permeable channel. For research use only.

In response to pathogen-derived and proinflammatory stimuli, relocates from intracellular compartments to NK-dendritic cell and NK-macrophage immune synapses where it mediates ATP efflux and NK cell activation involved in antimicrobial and antitumor responses. May assemble to form gap junction channel-like structures with gating and ion conductance likely regulated by membrane lipids and voltage rather than by extracellular calcium levels.

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