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Human CANX Recombinant Protein (N-His)
Key Features

Human CANX Recombinant Protein (N-His) (GXRP01335)

SKU GXRP01335
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human CANX Recombinant Protein (N-His)

Human CANX Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning His21-Pro481, with an N-terminal His tag. Predicted molecular weight: 54.73 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Calnexin (CANX) is a ~67 kDa protein. Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. For research use only.

It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.

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