Description
Human CAVIN4 Recombinant Protein (N-His-KSI)
Human CAVIN4 Recombinant Protein (N-His-KSI) is a recombinant protein expressed in E. coli, spanning Glu25-Ser364, with an N-terminal His-KSI tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Caveolae-associated protein 4 is a ~41 kDa protein. Modulates the morphology of formed caveolae in cardiomyocytes, but is not required for caveolar formation. For research use only.
Facilitates the recruitment of MAPK1/3 to caveolae within cardiomyocytes and regulates alpha-1 adrenergic receptor-induced hypertrophic responses in cardiomyocytes through MAPK1/3 activation. Contributes to proper membrane localization and stabilization of caveolin-3 (CAV3) in cardiomyocytes. Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway.
| Product Name: | Human CAVIN4 Recombinant Protein (N-His-KSI) |
| SKU: | GXRP13773 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | CAVIN4, Caveolae-associated protein 4, MURC, Muscle-related coiled-coil protein, Muscle-restricted coiled-coil protein |
| Tag: | N-His-KSI |
| Expression Host: | E. coli |
| Protein Length: | Glu25-Ser364 |
| UniProt: | Q5BKX8 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
