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Human CBFA2T2 Recombinant Protein (N-His)
Key Features

Human CBFA2T2 Recombinant Protein (N-His) (GXRP13680)

SKU GXRP13680
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human CBFA2T2 Recombinant Protein (N-His)

Human CBFA2T2 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ala109-Asn213, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Protein CBFA2T2 is a ~67 kDa protein. Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. For research use only.

Via association with PRDM14 is involved in regulation of embryonic stem cell (ESC) pluripotency. Involved in primordial germ cell (PCG) formation. Stabilizes PRDM14 and OCT4 on chromatin in a homooligomerization-dependent manner. Can repress the expression of MMP7 in a ZBTB33-dependent manner.

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