Description
Human CCDC88A Recombinant Protein (N-His)
Human CCDC88A Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Phe223, with an N-terminal His tag. Predicted molecular weight: 27.85 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Girdin is a ~216 kDa protein. Bifunctional modulator of guanine nucleotide-binding proteins (G proteins). For research use only.
Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. Also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. Essential for cell migration. Interacts in complex with G(i) alpha subunits with the EGFR receptor, retaining EGFR at the cell membrane following ligand stimulation and promoting EGFR signaling which triggers cell migration.
| Product Name: | Human CCDC88A Recombinant Protein (N-His) |
| SKU: | GXRP11550 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | APE, Akt phosphorylation enhancer, CCDC88A, Coiled-coil domain-containing protein 88A, G alpha-interacting vesicle-associated protein, GIV, GRDN, Girders of actin filament, Girdin, HkRP1, Hook-related protein 1, KIAA1212 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Phe223 |
| Calculated MW: | 27.85 kDa |
| UniProt: | Q3V6T2 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |