Human CCN1 (YM1B) Antibody is a research-grade biosimilar monoclonal antibody targeting Insulin-like growth factor-binding protein 10. It is a human IgG antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
CCN family member 1 (CCN1/IGFBP10) is a ~42 kDa protein. Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CCN1-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.
Product Name:
Human CCN1 (YM1B) Antibody
SKU:
GXBS00975
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Clone:
YM1B
Target:
Insulin-like growth factor-binding protein 10
Isotype:
IgG
Host Species:
Human
Reactivity:
Human
Applications:
ELISA, FACS, Functional assay, Research in vivo
Expression Host:
Mammalian cells
Synonyms:
YM1B
Purity:
>95% purity as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
![Anti-CYR61/CCN1 [6H8-N6-L7] Monoclonal Antibody (AGMB04874)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/276159/676624/anti-cyr61ccn1-6h8-n6-l7-monoclonal-antibody-agmb04874__52015.1773030025.jpg?c=2 "Anti-CYR61/CCN1 [6H8-N6-L7] Monoclonal Antibody (AGMB04874)")