Description
Human CCN4 Recombinant Protein (N-His)
Human CCN4 Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Cys216-Arg347, with an N-terminal His tag. Predicted molecular weight: 16.94 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. CCN family member 4 (CCN4/WISP-1) is a ~40 kDa protein. Downstream regulator in the Wnt/Frizzled-signaling pathway. For research use only.
Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts.
| Product Name: | Human CCN4 Recombinant Protein (N-His) |
| SKU: | GXRP00307 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | WNT1-inducible-signaling pathway protein 1, WISP-1, Wnt-1-induced secreted protein, CCN4, WISP1, CCN family member 4 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Cys216-Arg347 |
| Calculated MW: | 16.94 kDa |
| UniProt: | O95388 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only. |
