Description
Human CCNH Recombinant Protein (N-His)
Human CCNH Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Met1-Leu323, with an N-terminal His tag. Predicted molecular weight: 39.81 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cyclin-H is a ~37 kDa protein. Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. For research use only.
CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
| Product Name: | Human CCNH Recombinant Protein (N-His) |
| SKU: | GXRP11362 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | Human |
| Synonyms: | CCNH, Cyclin-H, MO15-associated protein, p34, p37 |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Met1-Leu323 |
| Calculated MW: | 39.81 kDa |
| UniProt: | P51946 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
