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Human CCNY Recombinant Protein (N-His)
Key Features

Human CCNY Recombinant Protein (N-His) (GXRP13846)

SKU GXRP13846
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human CCNY Recombinant Protein (N-His)

Human CCNY Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asn115-Asn286, with an N-terminal His tag. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Cyclin-Y is a ~39 kDa protein. Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. For research use only.

Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.

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