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Human CD108/SEMA7A Recombinant Protein (N-His)
Key Features

Human CD108/SEMA7A Recombinant Protein (N-His) (GXRP07253)

SKU GXRP07253
Product Type Recombinant Protein
Species Human
Expression System E. coli
Tag N-His
$458 - $2,412

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Description

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Human CD108/SEMA7A Recombinant Protein (N-His)

Human CD108/SEMA7A Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Asp65-Thr399, with an N-terminal His tag. Predicted molecular weight: 40.04 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Semaphorin-7A (CD108/SEMA7A) is a ~74 kDa protein. Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. For research use only.

Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of pro-inflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb.

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